Vasileios Christopoulos
Former Member of the Brain Sciences CenterBrain Sciences Center (BSC)

Publications

  1. Neural mechanisms underlying the exploration of small city maps using magnetoencephalography Experimental Brain Research (2015, November) Sakellaridi S, Christova P, Christopoulos V, Leuthold A, Peponis J, & Georgopoulos AP
  2. The effect of Apolipoprotein EApolipoprotein E (ApoE)a plasma lipoprotein discovered in 1973 (Shore and Shore 1973). It binds low-density lipoprotein receptors, thereby facilitating cellular lipoprotein exchange and metabolism. The human apoE polypeptide consists of 299 amino acids and comprises three polymorphisms resulting from single amino acid substitutions. Three isoforms (E4, E3, and E2) are the result of cysteine^aEUR"arginine interchanges at two sites, namely residues 112 and 158; however, other genetic variants have been described. These three isoforms, each differentially affecting protein function, result in six phenotypes: three homozygotes (E4/4, E3/3, E2/2) and three heterozygotes (E4/3, E4/2, E3/2). With respect to the number of cysteine residues per mole, E2/2 contains 4, E3/2 contains 3, E4/2 and E3/3 each contain 2, E4/3 contains 1, and E4/4 contains 0. The number of cysteine residues per mole (CysR/mole) provides a numerical, biochemical scale in lieu of the genotype-based categories.4 on Synchronous Neural InteractionsSynchronous Neural Interactions (SNI)Zero-lag partial correlations in pairs of MEG time series and denote the strength and polarity (positive or negative) of neuronal interactions. Anomalies in SNIs as assessed by MEG differentiate psychiatric disorders from healthy brain functioning and can discriminate among various brain diseases. From this research, a highly distinctive, unique PTSD SNI signature characterized by miscommunication of temporal and parietal and/or parieto-occipital right hemispheric areas with other brain areas has emerged. These findings, in addition to the growing research applying MEG to other psychiatric disorders, highlight the utility of MEG in identifying biomarkers of disease and underscore the potential for broader clinical applications of MEG. in brain cultures Experimental Brain Research (2015, June) Christopoulos V, Georgopoulos A, & Georgopoulos AP
  3. Cognitive mechanisms underlying instructed choice exploration of small city maps Frontiers in Neuroscience (2015, March) Sakellaridi S, Christova P, Christopoulos V, Vialard A, Peponis J, & Georgopoulos AP
  4. Spatiotemporal neural interactions underlying continuous drawing movements as revealed by magnetoencephalography Experimental Brain Research (2012, October) Christopoulos V, Leuthold A, & Georgopoulos AP
  5. Independent Component Analysis and Evolutionary Algorithms for Building Representative Benchmark Subsets IEEE - International Symposium on Performance Analysis of Systems and Software (2008, May) Christopoulos V, Lilja DJ, Schrater PR, & Georgopoulos AP