Art Leuthold, PhD
Magnetoencephalography Magnetoencephalography (MEG)A noninvasive technique that detects magnetic fields above the surface of the head produced by postsynaptic potentials in the brain. Site Manager, Brain Sciences CenterBrain Sciences Center (BSC)
Physicist, Minneapolis VA Medical CenterVA Medical Center (VAMC)
Assistant Professor Neuroscience, University of Minnesota
Physicist, Minneapolis VAMCVA Medical Center (VAMC)

leuth004@umn.edu

Education
PhD, Medical Physics, University of Wisconsin
MS, Medical Physics, University of Wisconsin
BS, Physics, Chemistry, University of Wisconsin

Specialty/Focus
MEGMagnetoencephalography (MEG)A noninvasive technique that detects magnetic fields above the surface of the head produced by postsynaptic potentials in the brain. signal processing and methods development aimed at the study of basic brain systems

Publications

Pages: 1March 2023 through January 20132October 2012 through November 20053November 2005 through September 1994
  1. The SNISynchronous Neural Interactions (SNI)Zero-lag partial correlations in pairs of MEG time series and denote the strength and polarity (positive or negative) of neuronal interactions. Anomalies in SNIs as assessed by MEG differentiate psychiatric disorders from healthy brain functioning and can discriminate among various brain diseases. From this research, a highly distinctive, unique PTSD SNI signature characterized by miscommunication of temporal and parietal and/or parieto-occipital right hemispheric areas with other brain areas has emerged. These findings, in addition to the growing research applying MEG to other psychiatric disorders, highlight the utility of MEG in identifying biomarkers of disease and underscore the potential for broader clinical applications of MEG. test as a functional neuromarker for PTSDPost-traumatic Stress Disorder (PTSD)A complex psychiatric syndrome that develops in response to trauma exposure. Individuals with PTSD experience intrusive recollections or reexperiencing of the traumatic event, avoidance of trauma reminders, emotional numbing, and hyperarousal. In addition, PTSD is associated with high rates of concomitant physical and mental health problems, increased health care use, and impairment in social and occupational functioning. Almost 7% of the general population and up to 30% of veterans meet lifetime criteria for PTSD. Indeed, PTSD is one of the most common psychiatric disorders, representing a significant and costly public health concern.: a robust classification method based on the bootstrap Journal of Neural Engineering (2010, January) Georgopoulos AP, Tan HRM, Lewis S, Leuthold A, Winskowski AM, Lynch J, & Engdahl B