Effie C. Tsilibary, MD PhD
Former Member of the Brain Sciences CenterBrain Sciences Center (BSC)

Publications

Pages: 1August 2021 through August 2016 • 2July 2016 through December 2007 • 3November 2007 through December 1993 • 4May 1993 through June 1985 • 5November 1983 through May 1977
  1. High Glucose Impairs Insulin Signaling in the Glomerulus: An In Vitro and Ex Vivo Approach PLoS ONE (2016, July) Katsoulieris EN, Drossopoulou GI, Kotsopoulou ES, Vlahakos V, Lianos EA, & Tsilibary EC
  2. Nephrin, a transmembrane protein, is involved in pancreatic beta-cell survival signaling Molecular and Cellular Endocrinology (2015, January) Kapodistria K, Tsilibary EC, Politis P, Moustardas P, Charonis AS, & Kitsiou P
  3. Neuroprotective role of MMP-9 overexpression in the brain of Alzheimer's 5xFAD mice Neurobiology of Disease (2014, October) Fragkouli A, Tsilibary EC, & Tzinia A
  4. Effect of nanostructured TiO2 crystal phase on photoinduced apoptosis of breast cancer epithelial cells International Journal of Nanomedicine (2014, April) Lagopati N, Tsilibary EC, Falaras P, Papazafiri P, Pavlatou EA, Kotsopoulou E, & Kitsiou P
  5. Chapter 6 - Neural ECM proteases in learning and synaptic plasticity Progress in Brain Research (2014, January) Tsilibary EC, Tzinia A, Radenovic L, Stamenkovic V, Lebitko T, Mucha M, Pawlak R, Frischknecht R, & Kaczmarek L
  6. Chapter 10 - ECM in brain aging and dementia Progress in Brain Research (2014, January) Morawski M, Filippov M, Tzinia A, Tsilibary EC, & Vargova L
  7. Calcitonin-induced NF-κB Activation Up-regulates Fibronectin Expression in MG63 Osteosarcoma Cells International Journal of Cancer Research and Treatment (2013, November) Tsagaraki I, Phenekos C, Tsilibary EC, & Tzinia A
  8. Glucose-induced gradual phenotypic modulation of cultured human glomerular epithelial cells may be independent of Wilms' tumor 1 BMC Molecular and Cell Biology (2013, June) Tsotakos NE, Sagnou M, Kotsopoulou ES, Tsilibary EC, & Drossopoulou GI
  9. Vitamin D Receptor Activators Upregulate and Rescue Podocalyxin Expression in High Glucose-Treated Human Podocytes Experimental Nephrology (2013, April) Verouti SN, Tsilibary EC, Demopoulos CA, Charonis AS, Charonis S, & Drossopoulou GI
  10. Oleuropein, an Anti-oxidant Polyphenol Constituent of Olive Promotes α-Secretase Cleavage of the Amyloid Precursor Protein (AβPP) Cellular and Molecular Neurobiology (2012, October) Kostomoiri M, Fragkouli A, Sangou M, Skaltsounis LA, Pelecanou M, Tsilibary EC, & Tzinia A
  11. An Apolipoprotein EApolipoprotein E (ApoE)a plasma lipoprotein discovered in 1973 (Shore and Shore 1973). It binds low-density lipoprotein receptors, thereby facilitating cellular lipoprotein exchange and metabolism. The human apoE polypeptide consists of 299 amino acids and comprises three polymorphisms resulting from single amino acid substitutions. Three isoforms (E4, E3, and E2) are the result of cysteine^aEUR"arginine interchanges at two sites, namely residues 112 and 158; however, other genetic variants have been described. These three isoforms, each differentially affecting protein function, result in six phenotypes: three homozygotes (E4/4, E3/3, E2/2) and three heterozygotes (E4/3, E4/2, E3/2). With respect to the number of cysteine residues per mole, E2/2 contains 4, E3/2 contains 3, E4/2 and E3/3 each contain 2, E4/3 contains 1, and E4/4 contains 0. The number of cysteine residues per mole (CysR/mole) provides a numerical, biochemical scale in lieu of the genotype-based categories.4 fragment affects matrix metalloproteinase 9, tissue inhibitor of metalloproteinase 1 and cytokine levels in brain cell lines Neuroscience (2012, May) Dafnis I, Tzinia AK, Tsilibary EC, Zannis VI, & Chroni A
  12. Enhanced neuronal plasticity and elevated endogenous sAPPα levels in mice over-expressing MMP9 Journal of Neurochemistry (2011, December) Fragkouli A, Paptheodoropoulos C, Georgopoulos S, Stamatakis A, Stylianopoulou F, Tsilibary EC, & Tzinia AK
  13. Matrix Metalloproteinase-9 Participates in NGF-Induced α-Secretase Cleavage of Amyloid-β Protein Precursor in PC12 Cells Journal of Alzheimer's Disease (2011, January) Fragkouli A, Tzinia AK, Charalampopoulos I, Gravanis A, & Tsilibary EC
  14. TIMP-1 interaction with αvβ3 integrin confers resistance to human osteosarcoma cell line MG-63 against TNF-α-induced apoptosis Cell and Tissue Research (2010, August) Tsagaraki I, Tsilibary EC, & Tzinia AK
  15. Rapid magnetic heating treatment by highly charged maghemite nanoparticles on Wistar rats exocranial glioma tumors at microliter volume Biomicrofuidics (2010, June) Rabias I, Tsitrouli D, Karakosta E, Kehagias T, Diamantopoulos G, Fardis M, Stamopoulos D, Maris TG, Falaras P, Zouridakis N, Diamantis N, Panayotou G, Verganelakis DA, Drossopoulou GI, Tsilibary EC, & Papavassiliou G
  16. High glucose induces suppression of insulin signalling and apoptosis via upregulation of endogenous IL-1β and suppressor of cytokine signalling-1 in mouse pancreatic beta cells Cellular Signalling (2010, May) Venieratos PD, Drossopoulou GI, Kapodistria KD, Tsilibary EC, & Kitsiou PV
  17. An ApoEApolipoprotein E (ApoE)a plasma lipoprotein discovered in 1973 (Shore and Shore 1973). It binds low-density lipoprotein receptors, thereby facilitating cellular lipoprotein exchange and metabolism. The human apoE polypeptide consists of 299 amino acids and comprises three polymorphisms resulting from single amino acid substitutions. Three isoforms (E4, E3, and E2) are the result of cysteine^aEUR"arginine interchanges at two sites, namely residues 112 and 158; however, other genetic variants have been described. These three isoforms, each differentially affecting protein function, result in six phenotypes: three homozygotes (E4/4, E3/3, E2/2) and three heterozygotes (E4/3, E4/2, E3/2). With respect to the number of cysteine residues per mole, E2/2 contains 4, E3/2 contains 3, E4/2 and E3/3 each contain 2, E4/3 contains 1, and E4/4 contains 0. The number of cysteine residues per mole (CysR/mole) provides a numerical, biochemical scale in lieu of the genotype-based categories.4 fragment can promote intracellular accumulation of amyloid peptide beta 42 Journal of Neurochemistry (2010, April) Dafnis I, Stratikos E, Tzinia AK, Tsilibary EC, Zannis VI, & Chroni A
  18. Impaired transcription factor interplay in addition to advanced glycation end products suppress podocalyxin expression in high glucose-treated human podocytes American Journal of Physiology - Renal Physiology (2009, September) Drossopoulou GI, Tsotakos NE, & Tsilibary EC
  19. Selective binding of integrins from different renal cell types to the NC1 domain of alpha3 and alpha1 chains of type IV collagen Journal of Nephrology (2009, January) Aggeli AS, Kitsiou PV, Tzinia AK, Boutaud A, Hudson BG, & Tsilibary EC
  20. Abeta(1-40)-induced secretion of matrix metalloproteinase-9 results in sAPPalpha release by association with cell surface APP Neurobiology of Disease (2007, December) Talamagas AA, Efthimiopoulos Spiros, Tsilibary EC, Figueiredo-Pereira ME, & Tzinia AK